Psychology Today | 02.01.2026 02:06
Major depressive disorder (MDD) affects about 10.4 percent of adults in one year and 20.6 percent over a lifetime (Hasin, 2018). Unfortunately, by themselves, psychotherapy and antidepressants only achieve full relief from symptoms in about 38 percent of treated patients. Combining psychotherapy and antidepressants modestly improves the outcomes.